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Principi farmacodinamici e farmacocinetici dello switch ...

Clinical psychopharmacotherapy365 Journal of Psychopathology 2013;19:365-374 SummaryObjectivesA correct switch between two antipsychotics, carried out to overcome suboptimal efficacy or the onset of adverse effects of a drug, is a relatively difficult task. The purpose of this review is to present the main aspects that psychiatrists have to consider planning a switch between antipsychotics. In particular, the is-sues concerning the switch from first and second generation an-typychotics to asenapine, the latest second generation available molecule, have been search on the main articles on the switch between antispy-chotics published after 2005, and particularly in the last years, was made on Pubmed and Medline.

Clinical psycoparmacoterapy Journal of Psychopathology 2013;19:365-374 365 Summary Objectives A correct switch between two antipsychotics, carried out to

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