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Principles of MALDI-TOF mass spectrometry

Purdue-UAB Botanicals Center for Age-Related DiseasePrinciples of MALDIP rinciples of MALDI--TOF TOF mass spectrometrymass spectrometryStephen Barnes, Botanical Center Workshop 2002 mass spectrometry Methods in Botanicals ResearchShining the light on samplesShining the light on samplesPurdue-UAB Botanicals Center for Age-Related Disease A focused laser beam, either in the UV or infra-red ranges, can evaporate compounds from the solid phase The resulting ions are injected into a tube (1 -2 m in length), accelerated and allowed to drift towards a detector.

Mass Spectrometry Methods in Botanicals Research. Shining the light on samples. ... time-of-flight. is proportional to their (MW) 1/2. Matrix-Assisted Laser Desorption Ionization (MALDI) Accelerating pulse detector. Short laser pulse. Flight tube …

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