Transcription of Protein-Protein Interactions: Stability, Function and ...
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Protein-Protein Interactions: Stability, Function and ...
Protein-Protein Interactions: Stability, Function and LandscapeStructural Aspects of Protein-Protein interactions Agenda Understand the importance of studying Protein-Protein interactions at the structural level Classify the various types of interactions Look at one structure-based method for predicting Protein-Protein interactionsLINKP rotein interaction Definition Specific interactions between two or more proteins. Examples Enzyme-inhibitor complex; antibody-antigen complex; receptor-ligand interactions , multiprotein complexes such as ribosomes or RNA usuallypermanentand optimized ( , thehomodimer cytochrome c9 (1)) (Fig. 1a).Heterocomplexes can also have suchproperties, or they can be non-obligatory,being made and broken according to theenvironment or external factors and involveproteins that must also exist independently[ , the enzyme inhibitorcomplex trypsin with the inhibitor frombitter gourd (2) (Fig.)]
Agenda • Understand the importance of studying protein-protein interactions at the structural level • Classify the various types of interactions
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