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Protein Structure - particlesciences.com

L-ArginineArgRL-LysineLysKL-HistidineHis HFigure 1 Particle Sciences QL-GlutamineGlnL-ThreonineThrTL-Methioni neMetMH2 ONL-IsoleucineIleIAsnNL-AsparagineL-Prol ineProPL-TyrosineTyrYL-Aspartic acidAspDL-Glutamic acidGluEGlycineGlyGL-AlanineAlaAL-Trypto phanTrpWL-PhenylalaninePheFCysCL-Cystein eL-LeucineLeuLL-ValineValVL-SerineSerSOH 2NH2 NBasicAcidicNeutralOOOHH2NH2 NOOHOOOHNH2H NH2 NNHHNNHNH2 ONH2 ONH2 OHONH2 OHONOHH2 ONH2 ONH2 ONH2 ONH2 SHONH2 OHOHOHOHOHOHOHOHOHOHOHOHOHOHOHOHOHOHOHON H2 ONHONH2 NOSOOH2NH2 NNH2 OOH2 NProtein StructureTechnical Brief 2009 Volume 8 Increasingly, drug developers are looking to large molecules and partic-ularly proteins as a therapeutic option. Formulation of a Protein drug product can be quite a challenge, but without a good understanding of the nature of Protein Structure and the conforma-tional characteristics of the specific Protein being formulated, the results can be ruinous.

Particle Sciences Figure 2 H H N HO O C N C H C O N N N N N N N N C H H H H H H H H C O C C C C C C C C O C O C O C O C O C O C O N N H C C O O C O N H N C H C C O C O N H H C CC C O O O N H C C C O N H H 3894 Courtney Street

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