Transcription of Protocol Recommendations for Use of …
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Protocol Recommendations for Use of …
Protocol Recommendations FOR. USE OF METHOTREXATE AND. MISOPROSTOL IN EARLY ABORTION. INTRODUCTION: Both methotrexate and misoprostol have been approved by the Food and Drug Administration (FDA) for purposes unrelated to abortion. Administration of methotrexate and misoprostol for induction of abortion in very early pregnancy has been reported in the medical literature, and the scientific evidence indicates that it is safe and efficacious for this use. Clinicians can prescribe methotrexate and misoprostol at their discretion for this off-label use. These Protocol Recommendations were initially developed at a meeting convened by the National Abortion Federation (NAF) and Planned Parenthood Federation of America (PPFA) on June 6, 1996. It was attended by the leading researchers who have published in this field as well as clinicians experienced with medical abortion techniques. These Recommendations have been updated to reflect the use of methotrexate and misoprostol as supported by the current evidence in the medical literature.
INTRODUCTION: Both methotrexate and misoprostol have been approved by the U.S. Food and Drug Administration (FDA) for purposes unrelated to abortion.
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