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PT, INR, and APTT Testing

Volume XXIII Issue 2 March/April 2018. PT, INR, and APTT Testing by Lori Eschenbacher, BSMT(ASCP)CLS(NCA) tors oral anticoagulant therapy ( , Coumadin). This test Washington State DOH, Lab Quality Assurance may also be ordered for patients suspected of DIC, liver failure, and Vitamin K deficiencies. M. illions of Americans take oral anticoagulant therapy ( , Coumadin). For each of these pa- The PT test evaluates the extrinsic tissue factor pathway tients, the Prothrombin Time (PT), International and common pathways of the coagulation cascade VII, X, Normalized Ration (INR), and Activated Partial Throm- V, II, and I (fibrinogen). The PT test is reported in seconds. boplastin Time (APTT) are the laboratory tests performed to achieve and monitor the appropriate medication dosage.

The INR result is the patient's PT result in seconds divided by the geometric mean of the PT result of the laboratory's normal patients, as calculated by each laboratory. ... acute phase reactants that are elevated in times of stress, and inflammation can …

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