Transcription of PT, INR, and APTT Testing
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PT, INR, and APTT Testing
Volume XXIII Issue 2 March/April 2018. PT, INR, and APTT Testing by Lori Eschenbacher, BSMT(ASCP)CLS(NCA) tors oral anticoagulant therapy ( , Coumadin). This test Washington State DOH, Lab Quality Assurance may also be ordered for patients suspected of DIC, liver failure, and Vitamin K deficiencies. M. illions of Americans take oral anticoagulant therapy ( , Coumadin). For each of these pa- The PT test evaluates the extrinsic tissue factor pathway tients, the Prothrombin Time (PT), International and common pathways of the coagulation cascade VII, X, Normalized Ration (INR), and Activated Partial Throm- V, II, and I (fibrinogen).
boplastin Time (APTT) are the laboratory tests performed to achieve and monitor the appropriate medication dosage. These tests are also used to assess unexplained bleeding or clotting. This article will discuss five basic areas: 1) basic coagulation terms, 2) basic requirements for changing lot numbers, 3) some examples of interfering substances,
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