Transcription of PT, INR, and APTT Testing
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PT, INR, and APTT Testing
Volume XXIII Issue 2 March/April 2018. PT, INR, and APTT Testing by Lori Eschenbacher, BSMT(ASCP)CLS(NCA) tors oral anticoagulant therapy ( , Coumadin). This test Washington State DOH, Lab Quality Assurance may also be ordered for patients suspected of DIC, liver failure, and Vitamin K deficiencies. M. illions of Americans take oral anticoagulant therapy ( , Coumadin). For each of these pa- The PT test evaluates the extrinsic tissue factor pathway tients, the Prothrombin Time (PT), International and common pathways of the coagulation cascade VII, X, Normalized Ration (INR), and Activated Partial Throm- V, II, and I (fibrinogen).
When performing the calculation, the values for the patient PT and the PT normal range mean value contain one deci-mal place (e.g., 12.0) and ISI includes two decimal places (e.g., 1.05). The INR should be rounded and reported to one decimal place (e.g., 2.5). ISI: The International Sensitivity Index (ISI) reflects the
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