Transcription of PT, INR, and APTT Testing
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PT, INR, and APTT Testing
Volume XXIII Issue 2 March/April 2018. PT, INR, and APTT Testing by Lori Eschenbacher, BSMT(ASCP)CLS(NCA) tors oral anticoagulant therapy ( , Coumadin). This test Washington State DOH, Lab Quality Assurance may also be ordered for patients suspected of DIC, liver failure, and Vitamin K deficiencies. M. illions of Americans take oral anticoagulant therapy ( , Coumadin). For each of these pa- The PT test evaluates the extrinsic tissue factor pathway tients, the Prothrombin Time (PT), International and common pathways of the coagulation cascade VII, X, Normalized Ration (INR), and Activated Partial Throm- V, II, and I (fibrinogen). The PT test is reported in seconds. boplastin Time (APTT) are the laboratory tests performed to achieve and monitor the appropriate medication dosage. INR: Differences in thromboplastin reagents have caused These tests are also used to assess unexplained bleeding or problems when comparing PT results across laboratories clotting. due to varying sensitivities of different thromboplastin reagents used in the PT test.
The PT test evaluates the extrinsic “tissue factor” pathway and common pathways of the coagulation cascade VII, X, V, II, and I (fibrinogen). The PT test is reported in seconds. INR: Differences in thromboplastin reagents have caused problems when comparing PT results across laboratories due to varying sensitivities of different thromboplastin
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