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Pulmonary Nodules: When to worry, when to ‘chill’

Pulmonary Nodules: When to worry, when to chill Douglas ArenbergAssociate ProfessorPulmonary & Critical CareDisclosure MDCH Grant Funds to improve tobacco cessation service in the Michigan Medicine Health System Past paid service Consultant/Advisory panel member for Nucleix, a company developing lung cancer biomarkers I will not be discussing anyspecific products or medications relevant to either of these financial relationshipsObjectives Recognize features of the patient and the nodule that predict a likelihood of malignancy Understand the indications for (and limitations of) lung nodule biopsyLet s start with an exercise Each of the next few slides has two nodules found on CT scans There are some differences between the nodules Select which one you think is more likely to be malignant (A or B), and (in your head) think of one or two words why you chose your answer Which of these is more likely malignant?ABWhich of these is more likely malignant?ABWhich of these is more likely malignant?

for Nucleix, a company developing ... Low probability Intermediate Probability High probability. What do we do with this “probability”? Definitely Benign Definitely Malignant ... Upper lobe FDG-avid on PET Low probability ~5-15% or less Intermediate Probability High Probability >60%.

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  Company, Intermediate, Upper

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