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QUALITATIVE AND QUANTITATIVE COMPOSITION

VA10-1_5 Dec16 SUPERSEDES: vA9-1_21 Jun16 Page 1 of 18 zyprexa (olanzapine) NAME OF THE MEDICINE zyprexa (olanzapine). zyprexa ZydisTM (olanzapine). Chemically, olanzapine is 2-methyl-4-(4-methyl-1-piperazinyl)-10H- thieno[2,3-b] [1,5]benzodiazepine and its empirical formula is C17H20N4S. Olanzapine is a yellow crystalline solid, practically insoluble in water with a molecular weight of The CAS number for olanzapine is 132539-06-1. Olanzapine has the following structural formula: N N S CH3 N N CH3 H 2 3 4 5 6 7 8 9 101 1'2'3'4'5'6' DESCRIPTION zyprexa Tablets: zyprexa tablets are white, film coated tablets for oral administration. The active ingredient in zyprexa tablets is olanzapine. zyprexa tablets also contain excipients: lactose, hyprolose, crospovidone, microcrystalline cellulose, magnesium stearate, hypromellose and carnauba wax.

Acute mania associated with bipolar disorder The recommended starting dose for ZYPREXA is 10 or 15 mg administered once a day as monotherapy or 10 mg administered ...

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