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QUANTITATIVE ESTIMATION OF LOSARTAN …

IJRPC 2011, 1(3) Rajesh et al. ISSN: 2231 2781 295 INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACY AND CHEMISTRY Available online at QUANTITATIVE ESTIMATION OF LOSARTAN potassium IN PHARMACEUTICAL DOSAGE FORMS BY UV SPECTROPHOTOMETRY Rao PLKM, Venugopal V, Anil Kumar G, Rajesh B*, Prasad GAL and Ravindergoud D Department of Pharmaceutical Analysis, SLC s college of Pharmacy, Hyderabad, Andhra Pradesh, India. *Corresponding Author: INTRODUCTION LOSARTAN potassium (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5- yl) biphenyl-4-yl] methyl}-1H-imidazol-5-yl) methanol is used in the treatment of hypertension. Structure of LOSARTAN Second Derivative Spectroscopy The second derivative spectrum characterised by two satellite maxima and an inverted band of which the minimum corresponds to the -max of the fundamental band. Experimental Method UV Visible Spectroscopy Insrument Labindia Ltd. UV 3000+, with bandwidth of 1nm, wavelength accuracy of and matched quartz cells are used.

IJRPC 2011, 1(3) Rajesh et al. ISSN: 2231 2781 295 INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACY AND CHEMISTRY Available online at www.ijrpc.com QUANTITATIVE ESTIMATION OF LOSARTAN POTASSIUM IN

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  Potassium, Losartan potassium, Losartan

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