Transcription of Ranitidini hydrochloridum - uspbpep.com
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Ranitidini hydrochloridum - uspbpep.com
EUROPEAN PHARMACOPOEIA hydrochloride04/2005:0946 RANITIDINE HYDROCHLORIDER anitidini [2-[[[5-[(Dimethylamino)methyl]furan-2-y l]methyl]sulphan-yl]ethyl]-N -methyl-2-nitroethene-1,1-diamine : per cent to per cent (dried substance).CHARACTERSA ppearance: white or pale yellow, crystalline : freely soluble in water, sparingly soluble orslightly soluble in anhydrous ethanol, very slightly solublein methylene shows Infrared absorption spectrophotometry ( ).Comparison:ranitidine hydrochloride the spectra show differences, dissolve 10 mg of thesubstance to be examined and 10 mg of the referencesubstance separately in ml ofmethanol Rin anagate mortar. Evaporate to dryness under a stream ofnitrogen R. Dry the residues under vacuum for 30 3 drops ofliquid paraffin Rto the residues andtriturate until the mull shows a milky the mulls between 2 plates transparent toinfrared radiation and record new It gives reaction (a) of chlorides ( ).
EUROPEAN PHARMACOPOEIA 5.1 Ranitidine hydrochloride 04/2005:0946 RANITIDINE HYDROCHLORIDE Ranitidini hydrochloridum C13H23ClN4O3S Mr 350.9 DEFINITION N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]sulphan-
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