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Rational use of vaccination for prevention and control of ...

1 VOL 10 | MAY 2016 1 Abstract/overview1 Why opt for vaccination ?3 Principles of Rational vaccine use4 Key questions in designing a vaccination strategy for disease prevention and control6 Potential drawbacks of vaccine use7 Does use of vaccination lead to endemic infection?7 Conclusion8 ReferencesAbstract/overviewVaccination can play a valuable role in con-trol, prevention and elimination of highly pathogenic avian influenza (HPAI) viruses. In places where HPAI remains endemic, vaccine has been used to reduce the quantities of vi-rus shed into the environment, which, in turn, reduces human exposure and the likelihood of zoonotic and pandemic influenza, as well as the risk of severe disease in poultry . In other countries (China, Hong Kong SAR and Mexico), vaccination has been used successfully to as-sist in the elimination of virus.

3 V 10 | MA 2016 What vaccines are available? Two main types of poultry vaccine are availa-ble for avian influenza at present: killed anti-gen in an oil-based adjuvant and vaccines that

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