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research methods & reporting - consort …

BMJ | online FiRST | 1 of 28research methods & reporting The whole of medicine depends on the transparent report ing of clinical trials. 1 Well designed and properly executed randomised con trolled trials (RCTs) provide the most reliable evidence on the efficacy of healthcare interventions, but trials with inadequate methods are associated with bias, especially exaggerated treatment 5 Biased results from poorly designed and reported trials can mislead decision making in health care at all levels, from treatment decisions for a patient to formulation of national public health appraisal of the quality of clinical trials is possible only if the design, conduct, and analysis of RCTs are thor oughly and accurately described in the report.

Page 1 of 28 BMJ | online FiRST | bmj.com research methods & reporting “The whole of medicine depends on the transparent report ‑ ing of clinical trials.”1 Well designed and properly executed randomised con‑

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