Transcription of Review Antidepressant use in pregnancy: a critical review ...
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Review Antidepressant use in pregnancy: a critical review ...
ReviewAntidepressant use in pregnancy : a criticalreview focused on risks and controversiesByatt N, Deligiannidis KM, Freeman MP. Antidepressant use inpregnancy: a critical Review focused on risks and :Conflicting data have led to controversy regardingantidepressant use during pregnancy . The objectives of this study are toi) Review the risks of untreated depression and anxiety, ii) Review theliterature on risks of exposure to antidepressants during pregnancy , iii)discuss the strengths and weaknesses of the different study designs usedto evaluate those risks, and iv) provide clinical :MEDLINE/PubMed was searched for reports and studies onthe risk of first-trimester teratogenicity, postnatal adaptation syndrome(PNAS), and persistent pulmonary hypertension (PPHN) with in uteroantidepressant :While some individual studies suggest associations betweensome specific major malformations, the findings are , the absolute risks appear small.
priate control groups, iii) use blind raters of the neonates and iv) take into account maternal diagno- sis or symptoms or other confounding variables. † The evidence regarding the risk of PPHN because of in utero antidepressant exposure is inconclusive.
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