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RNA Processing: Eukaryotic mRNAs

Peter J. Russell, iGenetics: Copyright Pearson Education, Inc., publishing as Benjamin Cummings1 RNA processing : Eukaryotic mRNAs Eukaryotic mRNAs have three main parts (Figure ): 5! untranslated region (5! UTR), varies in length. The coding sequence specifies the amino acid sequence of the protein that will be produced duringtranslation. It varies in length according to the size of the protein that it encodes. 3! untranslated region (3! UTR), also varies in length and contains information influencing the stability of J. Russell, iGenetics: Copyright Pearson Education, Inc., publishing as Benjamin Cummings2 RNA processing In prokaryotes, no RNA processing is necessary: the nascent RNA is usually the mRNA. In eukaryotes, the nascent RNA is called primarytranscript-RNA needs to be processed and transported to the cytoplasm for translation to occur.

Peter J. Russell, iGenetics: Copyright © Pearson Education, Inc., publishing as Benjamin Cummings 13 Mechanism of Splicing ¥There is an intranuclear protein/RNA

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