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Sample Size - vanbelle.org

2 SampleSizeThe rstquestionfacedbya statisticalconsultant,andfrequentlythela st,is, Howmany subjects(animals,units)doI need? , TypeII error, andone sidedversustwo questionistosettlethetypeofvariable(endp oint)theconsulteehasinmind:Isit continuous,discrete,orsomethingelse?Forc ontinuousmeasurementsthenormaldistributi onisthedefaultmodel,fordistributionswith binaryoutcomes, samplesizecalculation,foroneortwo groups,are:TypeI Error( )Probabilityofrejectingthenullhypothesis whenit is trueTypeII Error( )Probabilityofnotrejectingthenullhypothe siswhenit is falsePower=1 Probabilityofrejectingthenullhypothesisw henit is false 20and 21 Variancesunderthenullandalternative hypothe ses(maybethesame) 0and 1 Meansunderthenullandalternative hypothesesn0andn1 Samplesizesintwo groups(maybethesame)Thechoiceofthealtern ative hypothesisis they knew thevalueofthealternative hypothesis,they wouldnotneedtodothestudy.

CALCULATING SAMPLE SIZE USING THE COEFFICIENT OF VARIATION 31 Lakatos (1998). One advantage of a power of 0.95 is that it bases the inferences on

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