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SARS-CoV-2 variants of concern and variants under ...

1 SARS-CoV-2 variants of concern and variants under investigation in England Technical briefing 17 25 June 2021 This briefing provides an update on previous briefings up to 18 June 2021 SARS-CoV-2 variants of concern and variants under investigation 2 Contents Summary .. 3 Published information on variants .. 4 Part 1: Surveillance overview .. 5 variants under surveillance .. 5 Variant prevalence .. 16 Secondary attack rates .. 24 Surveillance of reinfections .. 31 SARS-CoV-2 Immunity and Reinfection Evaluation (the SIREN study) cohort monitoring .. 31 variants linked to suspected SARS-CoV-2 outbreaks .. 34 Part 2: Delta ( ) 38 Severity .. 38 Monitoring of vaccine effectiveness .. 38 Surveillance through genomic data .. 40 Surveillance through S gene detection .. 47 PCR cycle threshold data.

genome sequencing and by a genotyping PCR test, including the categorisation of confirmed and probable variant results and a rules-based decision algorithm (RBDA) to identify variant and mutation (VAM) profiles from genotype assay mutation profiles. Genotyping is used to identify variants Alpha, Beta, Delta and Gamma; targets were

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