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SCIENTIFIC DISCUSSION This module reflects the …

1/22 EMEA 2004 SCIENTIFIC DISCUSSION this module reflects the initial SCIENTIFIC DISCUSSION for the approval of Forsteo. For information on changes after approval please refer to module 8. 1. Introduction Osteoporosis is a systemic disorder characterised by decreased bone mass and microarchitectural deterioration of bone tissue leading to bone fragility and increased susceptibility to fractures of the hip, spine and wrist. Osteoporosis affects an estimated 75 million people in Europe, United States and Japan combined.

1/22 EMEA 2004 SCIENTIFIC DISCUSSION This module reflects the initial scientific discussion for the approval of Forsteo. For information on changes after approval please refer to module 8.

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