Section5 - nes.scot.nhs.uk

29 Section 5 Factorsaffecti ng wa rfar inObjectivesOn co mplet ionofth is se ct ionyo u sh ould beableto: analys e thewid e ran geof factorsthatcanaff ect warfarintherapy summaris e th e mainfactors th at pharmacists an d pharmacytechniciansshoul d be particularly awareof(eg,druginteractions,di et, lifestyle) predi ct dr uganddiseasein te ra ct io nswi or s can af fe ct an indi vid ual s responseto warfarin, including: dr ug int eract io ns (i nc ludi ng he rbal remedies) diseasesta tes age preg nan cy diet alcoh ol con cord Dru g interactionsAlmostany dru g ca n inte rac t wi th warfar in. Interactionsinv olvi ng warfarin can bedivid ed int o two mai n groups: ph armacokinet ic ph rma cokineticeff ectsA ph armacokinet ic inte rac ti on is one that will alter the pla sma co ncent rationofwarfarinand res ult in a ch ang e in the IN R.

Section5 29 Factorsaffectingwarfarin Objectives On completion of this section you should be able to: analyse the wide range of factors that can affect warfarin therapy summarise the main factors that pharmacists and pharmacy technicians should be particularly aware of (eg, drug interactions,

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