Transcription of SEPARATION TECHNIQUES - uspbpep.com
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SEPARATION TECHNIQUES - uspbpep.com
Chromatographic SEPARATION techniquesEUROPEAN PHARMACOPOEIA , by passing the pressurised solvent through apulse-damping device. Tubing and connections are capableof withstanding the pressures developed by the controlled systems are capable of accuratelydelivering a mobile phase in either constant or varyingconditions, according to a defined programme. In the case ofgradient elution, pumping systems which deliver solvent(s)from several reservoirs are available and solvent mixing canbe achieved on either the low or high-pressure side of thepump(s).
EUROPEAN PHARMACOPOEIA 6.0 2.2.46. Chromatographic separation techniques Mass distribution ratio The mass distribution ratio (Dm) (also known as the capacityfactor k’ or retention factor k) is defined as: KC = equilibrium distribution coefficient (also known as distribution constant),
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