Transcription of SIGN 145 • Assessment, diagnosis and …
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SIGN 145 • Assessment, diagnosis and …
SIGN 145 assessment , diagnosis and interventions for autism spectrum disordersA national clinical guideline June 2016 EvidenceKEY TO EVIDENCE STATEMENTS AND RECOMMENDATIONSLEVELS OF EVIDENCE1++High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias1+Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias1 -Meta-analyses, systematic reviews, or RCTs with a high risk of bias2++ High-quality systematic reviews of case-control or cohort studies High-quality case-control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal2+Well-conducted case-control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal2 - Case-control or cohort studies with a high risk of confounding or bias and a significant risk that the relationship is not causal3 Non-analytic studies, eg case reports, case series4 Expert opinionRECOMMENDATIONSSome recommendations can be made with more certainty than others.
SIGN 145 • Assessment, diagnosis and interventions for autism spectrum disorders A national clinical guideline June 2016
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