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Slow-Stirring Method for Highly Hydrophobic …

Validation study Slow-Stirring Method for POW-determination 1 Ring TestProposal of the Netherlands for a new OECD guidelinePartition Coefficient n-Octanol/Water (POW) Slow-Stirring Method for Highly Hydrophobic ChemicalsValidation ReportRIVM contract-Nrs602730M/602700/01 Johannes TollsIRAS Environmental Toxicology and ChemistryUtrecht UniversityValidation study Slow-Stirring Method for POW-determination 2 Table of contentsThe validation 3 Annex 1 The validation management 9 Parties and 9 Persons 10 Annex 2 Original guideline proposal - Draft submitted to 11 Annex 3 - The validation study 25 Annex 4 Test compound selection and establishing reference 27 Number of test 27 Test compound 28 Derivation of log POW,ref 29 Annex 5 - Guideline for participants in the validation 31I.

Validation study ‘Slow-stirring method for POW-determination’ 1 Ring Test Proposal of the Netherlands for a new OECD guideline Partition Coefficient n-Octanol/Water (P OW)

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