SMARTImmunology - SmartAnalyst

Immunology Newsletter | January 2018 Volume 2, Issue 1. SMARTI mmunology The Immunology Newsletter from SmartAnalyst . IBD: Emerging Treatment Landscape Inflammatory bowel disease (IBD), comprising of ulcerative colitis (UC) and Crohn's disease (CD), is a complicated, uncontrolled, and multifactorial It is characterized by chronic, disabling, relapsing, or progressive idiopathic inflammation leading to mucosal damage that may involve the entire gastrointestinal tract. Common symptoms include abdominal pain, diarrhea, rectal bleeding, gut/ perianal fistulas or abscesses, weight loss, malnutrition, and ,3,4 Additionally, it may be associated with an increased risk of colitis-associated The chronic nature of inflammatory bowel disease (IBD) In the Western world, the incidence of UC is showing a has an enormous economic burden on patients, and the downward trend whereas incidence of CD is either constant treatment is far from optimal due to the limited understanding or shows a slight upward trend.

To o ocument 2 Crohn’s Disease (CD) can affect any part of the GI tract and 30-40% of the patients have disease limited to the small bowel, 40 …

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