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South African National TB Guidelines - Adults

South African National TB Guidelines - Adults WHO STARTS TB TREATMENT? MONITORING OF PATIENTS ON TB TREATMENT MANAGEMENT OF COMMON ADVERSE DRUG REACTIONS TO TB DRUGS. Patients who have bacteriological confirmation of TB: GeneXpert, AFB smear or TB culture Follow-up visits: 2 weeks after start of TB treatment, then monthly Side effects Drug (s) Management Patients with clinical signs and symptoms suggestive of TB (coughing, weight loss, night sweats and/or At every visit responsible fever) and radiological evidence with/without bacteriological confirmation TB symptoms (Refer to doctor if symptoms worsen) Anorexia, nausea, abdominal Rifampicin Exclude drug induced liver injury/hepatitis and other causes of gastrointestinal STANDARD TREATMENT OF NEW AND PREVIOUSLY TREATED TB FOR Weight (Adjust dosing accordingly.)

counselling the patient and identifying a treatment supporter Repeat smear at 11 weeks heck culture and DST results At 23 weeks: Take 1 sputum smear Drug Susceptible: Re-start T treatment, counsel the patient and provide treatment support Drug Resistant: Refer to MDR-T unit Negative and drug susceptible hange to continuation phase at end of week 12

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