Transcription of Structure-Function of the Glucagon Receptor Family …
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Structure-Function of the Glucagon Receptor Family …
Receptors and Channels, 8:179 188, 2002. Copyright c 2002 Taylor & Francis 1060-6823/02 $ + .00. DOI: Structure-Function of the Glucagon Receptor Family of G protein Coupled Receptors: The Glucagon , GIP, GLP-1, and GLP-2 Receptors P. L. Brubaker Departments of Physiology and Medicine, University of Toronto, Toronto, Ontario, Canada D. J. Drucker Department of Medicine, Banting and Best Diabetes Centre, Toronto General Hospital, Toronto, Ontario, Canada convertases results in the liberation of Glucagon in the pancreatic The Glucagon -like peptides include Glucagon , GLP-1, and A cell, and GLP-1 and GLP-2 in the intestinal L cell and brain GLP-2, and exert diverse actions on nutrient intake, gastrointesti- (Mojsov et al.)
STRUCTURE-FUNCTION OF G PROTEIN–COUPLED RECEPTORS 181 GLP-1 (GLP-1R) have demonstrated that loss of GIP or GLP-1 action results in an impaired insulin response to oral glucose
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