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Substance Abuse 1. Acute and Protracted …

Dependence, Addiction and Withdrawal1 Substance Abuse Protracted Withdrawal1 Kate Speck, PhD, MAC, LADCO verview1. Acute and Protracted Withdrawal2 Withdrawal Potential2. Withdrawal Potential 3. Recovery Reinforcers2 Addiction Addiction is a primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and 3pmanifestations. It is characterized by behaviors that include one or more of the following: impaired control over drug use, compulsive use, continued use despite harm, and Higher or more frequent dosing to achieve the initial effects of the drug Neuroadaption to continuously administered opioids Occurrence variable not always linked with4 Occurrence variable, not always linked with dependence Tolerance to non-analgesic effects beneficial Analgesic tolerance rarely the cause for dose escalation Dose escalation usually indicates disease change Tolerance does not imply addictionDependence Chronic medical condition Tolerance Withdrawal Lack of control Narrowing of behavior Continued use despite problems Need all or most of these symptoms to beconsidered drug dependentPhysical Dependence A state of neuroadaption manifested by a drug class-specific withdrawal syndrome Produced by

Dependence, Addiction and Withdrawal 1 Substance Abuse Protracted Withdrawal 1 Kate Speck, PhD, MAC, LADC Overview 1. Acute and Protracted Withdrawal

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