Transcription of SUGI 27: Generating Randomization Schedules Using SAS(r ...
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Paper 267-27 Generating Randomization Schedules Using SAS ProgrammingChunqin Deng and Julia Graz, PPD, Inc., Research Triangle Park, North CarolinaABSTRACTR andomization as a method of experimental control hasbeen extensively used in clinical trials. Generating therandomization schedule has been an essential part ofsome trials. We discuss how to use SAS programmingand SAS PROC PLAN to generate the randomizationschedule. The issues related to Randomization are alsodiscussed. Case studies are used to illustrate the use ofSAS programming and SAS PROC PLAN in generatingrandomization : Randomization Schedule, Clinical Trial,PROC PLANINTRODUCTIONR andomization as a method of experimental control hasbeen extensively used in clinical trials.
randomization schedule for a study with three arms (a new drug treatment, an active control treatment, and a placebo group). Suppose the sample size in the study is 360. We can write a program to generate the randomization schedule. In practice, block randomization is usually used in this type of study.
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