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Symptom Management Guidelines: XEROSTOMIA

Symptom Management guidelines : XEROSTOMIA Definition(s) XEROSTOMIA : abnormal dryness in the mouth characterized by a marked decrease and/or thickening of saliva, may be acute or chronic in nature. Contributing Factors Cancer Treatment Related Chemotherapy Agents Many chemotherapy agents have the potential to cause or contribute to XEROSTOMIA . Condition most often reverses post treatment. For specific chemotherapy information See Cancer Drug Manual in Resource Section Radiation Therapy Radiation to head and neck/salivary glands. Severity of saliva reduction is dependent upon total dose of radiation received, degree of salivary gland radiated, and individual patient variables Total body irradiation Surgical excision of salivary glands Graft versus host disease Medication(s) Anticholinergics ( atropine, transdermal scopolamine) Antipsychotics (( chlorpromazine, prochlorpromazine, risperidone) Antihistamines ( diphenhyrdamine, chlorpheniramine) Opioids Antispasmodics Antihypertensives Diuretics Antidepressants (Tricyclic-TCAs & Selective Serotonin Reuptake Inhibitors-SSRIs) Antiparkinsonians Bronchodilators Other Dehydration Immune disorders ( Sjogren s syndrome, HIV/AIDs) Alcohol or tobacco use)

Symptom Management Guidelines: XEROSTOMIA. Definition(s) • Xerostomia: abnormal dryness in the mouth characterized by a marked decrease and/or thickening of saliva, may be

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  Guidelines, Management, Symptom, Symptom management guidelines, Xerostomia

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