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TABLE OF CONTENTS - MD Anderson Cancer Center

Department of Clinical Effectiveness V16 Approved by Executive Committee of the Medical Staff on 09/15/2020 Page 1 of 24 Breast Cancer Invasive1 Stage I-III2 Disclaimer: This algorithm has been developed for MD Anderson using a multidisciplinary approach considering circumstances particular to MD Anderson s specific patient population, services and structure, and clinical information. This is not intended to replace the independent medical or professional judgment of physicians or other health care providers in the context of individual clinical circumstances to determine a patient's care. This algorithm should not be used to treat pregnant 2 Hormone receptor- 3 Hormone receptor-positive/HER2-positive or Hormone receptor- 4 Hormone receptor-negative/HER2-negative (triple negative breast Cancer )..Page 5 Evaluation During and Post Neoadjuvant 6 Radiation 8 Evaluation for Local 9 Appendix A: Genomic Considerations for Determination of Prognosis and Need for Adjuvant Chemotherapy in Patients with HR+ Breast 10 Appendix B: Neoadjuvant/Adjuvant Systemic Therapy 11 Appendix C: Endocrine Systemic Neoadjuvant/Adjuvant Therapy 12 Appendix D: Selection of Patients for Radiation to Regional 13 Appendix E: Recurrent Systemic Therapy Treatment 14 Principles of Breast Oncologic 15-17 Suggested 18-22 Development 23-24 1 There are special circumstances in which these guidelines do not apply.

Sep 15, 2020 · 2 See Genetic Counseling algorithm 3 See Physical Activity, Nutrition, and Tobacco Cessation algorithms; ongoing reassessment of lifestyle risks should be a part of routine clinical practice 4 Patients with signs or symptoms suggestive of metastatic disease should be considered for additional imaging

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