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TACO vs. TRALI - SEABB

taco vs . TRALI :Recognition, Differentiation, and Investigation of Pulmonary Transfusion ReactionsShealynn Harris, Assistant Medical DirectorAmerican Red Cross Blood ServicesSouthern RegionCase Presentation 74 year-old female with GI bleed Transfused 1 unit Apheresis Platelets 4 units RBCs During transfusion Difficulty breathing Hypoxia Increased respiratory rateConsiderations: Transfusion Reaction Pulmonary Transfusion Reaction Transfusion-associated circulatory overload (TACO) Transfusion-related acute lung injury ( TRALI ) Transfusion Reaction with Pulmonary Symptoms Allergic (anaphylaxis) Septic Transfusion ReactionOther Considerations Myocardial infarction Acute respiratory distress syndrome (ARDS) Sepsis Drug reaction PneumoniaChallenges in CharacterizingPulmonary Symptoms Associated with Transfusio

Transfusion-Related Acute Lung Injury (TRALI) Canadian TRALI Consensus Conference Definition •TRALI – New occurrence of acute onset acute lung injury (with

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