TB Guidelines.qxd 20/5/05 14:29 Page i

TB 20/5/05 14:29 Page iPreface & AcknowledgementsThe South African TUBERCULOSIS Control ProgrammePREFACEAt no time in recent history has tuberculosis been as great a concern as it is today. Despite highly effective drugs,morbidity and mortality due to Mycobacterium tuberculosis is increasing, a phenomenon that is being largelyfuelled by the HIV epidemic. Since the inception of the National TB Control Programme in 1996, there has beenan increase in case detection but with generally poor case holding marked by high interruption of treatment andloss of patients to follow not only increases the number of TB cases but also alters the clinical course of TB disease. Co-infected patients also suffer increased mortality mainly due to late diagnosis and other opportunistic infec-tions. Early diagnosis and effective treatment of TB among HIV-infected patients are critical for curing TB, min-imizing the negative effects of TB on the course of HIV and interrupting the transmission of M.

1 2 List of abbreviations The South African TUBERCULOSIS Control Programme Practical Guidelines 2004 AFB Acid-Alcohol Fast Bacilli AIDS Acquired Immune Deficiency Syndrome ART Antiretroviral Therapy BCG Bacille Calmette - Guerin CBO Community Based Organisation CHW Community Health Worker CDC Communicable Disease Coordinator DOH Department of Health DOT Directly-Observed …

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