Transcription of The Granulation Process 101 - Techceuticals
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The Granulation Process 101 - Techceuticals
His article presents the basic technologies for preparingpowders for tablet the Process ofcollecting particles together by creating bonds betweenthem. Bonds are formed by compression or by using abinding agent. If one were to make tablets from granulated sugarversus powdered sugar, for example, powdered sugar would bedifficult to compress into a tablet and granulated sugar wouldbe easy to compress. Powdered sugar s small particles have poorflow and compression characteristics. These small particleswould have to be compressed very slowly for a long period oftime to make a worthwhile tablet. Unless the powdered sugaris granulated, it could not efficiently be made into a tablet thathas good tablet characteristics such as uniform content or con-sistent hardness.
10 Pharmaceutical Technology TABLETING & GRANULATION 2002 www.pharmtech.com throughout the blend. The link between particles in each gran-ule must hold the particles together and keep them from break-ing apart before they are compressed.
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