The Handbook - Laboratory Diagnosis of Tuberculosis by ...

Laboratory Diagnosis of Tuberculosis by Sputum microscopy The Handbook Global edition A publication of the Global Laboratory Initiative a Working Group of the StopTB Partnership global Laboratory initiative advancing TB Diagnosis Published by SA Pathology Frome Road Adelaide South Australia 5000. All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means without the written permission of the publisher. The authors assert their moral rights in the work. ISBN: 978-1-74243-602-9. Production Project Editor Mark Fitz-Gerald Technical Editors Pawan Angra (CDC), Valentina Anisimova (KNCV), Christopher Gilpin (WHO), Richard Lumb (SA Pathology), Hiroko Matsumoto (JATA), Armand Van Deun (The Union). Manuscript Editors Mark Fitz-Gerald, Richard Lumb Illustrations Kerry Reid Design Sue Dyer Design Contact 2013 SA Pathology (formerly IMVS). Laboratory Diagnosis of Tuberculosis by Sputum microscopy Richard Lumb Armand Van Deun Ivan Bastian Mark Fitz-Gerald The Handbook Global edition Laboratory Diagnosis of Tuberculosis by Sputum microscopy Acknowledgements The writing team wish to thank the World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (The Union) for recognizing that smear microscopy remains an important tool for the Laboratory Diagnosis of Tuberculosis and in monitoring patients' response to treatment.

microscopy of two consecutive sputum specimens will identify the vast majority (95–98%) of smear-positive TB patients**. Moreover, microscopy can be decentralised to peripheral laboratories. Despite its advantages sputum smear microscopy does fall short in test sensitivity, especially for certain patient groups such as those living

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