Transcription of The Hematological Complications of Alcoholism
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The Hematological Complications of Alcoholism
People who abuse alcohol1are atrisk for numerous alcohol-relatedmedical Complications , includ-ing those affecting the blood ( , theblood cells as well as proteins presentin the blood plasma) and the bonemarrow, where the blood cells areproduced. (For more information onthe blood s composition and on thevarious types of blood cells and theirproduction, see sidebar, pp. 50 51.)Alcohol s adverse effects on the blood-building, or hematopoietic, system areboth direct and indirect. The directconsequences of excessive alcoholconsumption include toxic effects onthe bone marrow; the blood cell pre-cursors; and the mature red bloodcells (RBC s), white blood cells(WBC s), and platelets. Alcohol sindirect effects include nutritionaldeficiencies that impair the productionand function of various blood cells. These direct and indirect effects ofalcohol can result in serious medicalproblems for the drinker.
to either iron deficiency or excessively high levels of iron in the body. Because iron is essential to RBC functioning, iron deficiency, which is commonly caused by excessive blood loss, can result in anemia. In many alcoholic patients, blood loss and subsequent iron deficiency are caused by gastrointestinal bleeding.
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