The New AJCC 8th Edition Breast Cancer Staging

The New AJCC 8thEdition Breast Cancer StagingPrognostic Stage Groups & What They MeanMaui, Hawaii 2018 Susan C. Lester, , and Women s HospitalDana Farber Cancer InstituteHarvard Medical SchoolDisclosures My husband is head of translational medicine for the New Indication and Discovery Unit at will not be talking about any Novartis is Cancer Staging Important?For individual patients:Aids in estimating prognosis (survival) for individual patientsBreast cancerStage 0 (DCIS) >97% 20 year survivalStage IV (metastatic) <10% 20 year survivalGuides choices for local and systemic treatmentWhy is Cancer Staging Important?For the health care system and research: Organizes patients into similar groupsEssential for clinical studies, research studies, and epidemiologic studies Important for comparisons by location (country, state, institution), patient groups, and over timeTherefore, it is essential to stage Cancer consistently and accurately for optimal Cancer Denoix, MD (1912-1990)L Institut Gustave RoussyHe pioneered the Tumor Nodes Metastasis classification of was adopted by the Union for International Cancer Control (UICC) in

Although there were refinements, breast cancer staging remained substantially the same over ~60 years. A historical interlude . . . M etastasis (distant) ~5% of women with breast cancer have distant metastases at the time of first diagnosis in the US. Defines Stage IV.

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