Transcription of The Ominous Octet
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The Ominous Octet
The Ominous OctetHyperglycemiaInsulin secretionGlucagon secretionAlpha cellsBeta cellsGlucose productionIncretin effectLipolysisGlucose reabsorptionNeurotransmitter dysfunctionGlucose uptakeThe multiple complex pathophysiologic defects associated with type 2 diabetes mellitus require that multiple drugs be used in combination to improve the patient s overall outcomes, and that treatment should be based on reversal of all known complications, rather than strictly on reducing A1C. Early identifi cation and intervention is critical to prevent or slow the progressive -cell failure that already is well established in patients with impaired glucose : Adapted from DeFronzo RA. Am J Med. 2010;123(3 suppl)s38-s48 2013 ; fi lo; EraxionUnderstanding InsulinInsulin is a hormone that helps your body use the sugar (glucose) you get from the food you eat.
Understanding Insulin Insulin is a hormone that helps your body use the sugar (glucose) you get from the food you eat. Insulin levels rise and fall in response to the level of glucose in your blood.
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