Transcription of THE Rh BLOOD GROUP SYSTEM
{{id}} {{{paragraph}}}
Example: barber
THE Rh BLOOD GROUP SYSTEM
139 CHAPTER10139 THE Rh BLOOD GROUP SYSTEMCONNIE WESTHOFFThe Rh BLOOD GROUP SYSTEM is one of the mostpolymorphic and antigenic BLOOD GROUP sys-tems. It is second only to ABO in importance inblood transfusion and is well known as a primarycause of hemolytic disease of the fetus and newborn(HDFN). The principal antigen is D, and the termsRh positiveand Rh negativerefer to the presence orabsence of D antigen. Caucasians of European ex-traction have the highest incidence of the Rh-nega-tive phenotype (15% to 17%), and Rh-negative typeis much less common in Africa (5%) and Australiaand is considered a rare BLOOD type not routinelytested for in some parts of Asia ( 1%). Other com-mon Rh antigens include the antithetical C and c,and E and e antigens. Patients are not routinelytyped for these unless they have developed atypicalantibodies or are facing long-term transfusion sup-port for diseases such as myelodysplasia or sicklecell disease (SCD).
antigenic as blood with normal levels of D antigen, but donor units transfused to a patient who presents with anti-D after receiving Rh-negative blood (anti-G must be ruled out) should be reported to the donor facility so ... This results in loss of some D epitopes. The RBCs type
Loading..
Tags:
Information
Domain:
Source:
Link to this page:
Please notify us if you found a problem with this document: