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The Willowbrook Hepatitis Studies Revisited: Ethical Aspects

REVIEWS OF INFECTIOUS DISEASES * VOL. 8, NO. 1 * JANUARY-FEBRUARY 1986. ? 1986 by The University of Chicago. All rights reserved. 0162-0886/86/0801-0015$ SPECIALARTICLE. The Willowbrook Hepatitis Studies Revisited: Ethical Aspects Saul Krugman From the Departmentof Pediatrics,New YorkUniversity School of Medicine,New York,New York Studies of the natural history and prevention of viral Hepatitis were initiated at Willow- brook State School in 1955. During the subsequent two decades there was considerable controversyregardingthe Ethical Aspects of these Studies . The background of these Studies is described in detail in historical context. This report should provide the reader with in- formation needed to make an independent objective judgement of the ethics of the Wil- lowbrook Hepatitis Studies .

loran General Hospital in honor of the late Colonel Paul Stacey Halloran, a U.S. Army medical corpsman. After the war ended-in 1945, there was consider- 157 . 158 Krugman able political pressure to retain Halloran General Hospital as a Veterans Administration hospital. The

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