Transcription of Therapeutic Class Overview Benign Prostatic …
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Page 1 o f 6 Copyright 2014 Review Completed on 09/ 22/2014 Therapeutic Class Overview Benign Prostatic Hyperplasia Treatments Therapeutic Class Overview /Summary: The agents approved for the treatment of signs and symptoms of benignprostatic hyperplasia will be the focus of this review. The -adrenergic blockers including, alfuzosin,doxazosin, silodosin, tamsulosin, and terazosin, reduce smooth-muscle tone in the prostate andbladder neck decreasing lower urinary tract symptoms (LUTS) secondary to BPH. Alfuzosin, silodosinand tamsulosin are selective to the -adrenergic receptors located in the prostate and therefore areonly Food and Drug Administration (FDA) approved for BPH, whereas doxazosin and terazosinadditionally inhibit -adrenergic receptors found in the vascular smooth muscle and are additionallyindicated for The 5- reductase inhibitors, dutasteride and finasteride, are appropriatetreatment options for LUTS associated with overall Prostatic enlargement.
Treatment of signs and symptoms of benign prostatic hyperplasia, treatment of erectile dysfunction Tablet: 2.5 : 5 . 10 ¶
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