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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlikeLice nse. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this 2006, The Johns Hopkins University and Keith P. West, rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided AS IS ; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as DeficiencyIodine Deficiency Disorders(IDD)Most preventable cause of mental retardation in the worldKeith P. West, Jr., DrPHCenter for Human NutritionIodine Required to produce thyroid hormones that control cell metabolism, neuromuscular tissue growth and development, especially the fetal-perinatal brain Present in minute amounts (15-20 mg) in the body >90% of iodine stored in the thyroid Hormones Endocrine: produced & circulated to distant sites of action vs- Paracrine: act on neighboring cells Autocrine: act on same cells that produceIodine needed for thyroid hormones-Thyroxine (T4)- Tri
Iodine • Required to produce thyroid hormones that control cell metabolism, neuromuscular tissue growth and development, especially the fetal-
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