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Three neglected numbers in the CBC: The RDW, MPV, and …

Three neglected numbers in the CBC:The RDW, MPV, and NRBC countCLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 86 NUMBER 3 MARCH 2019167 The complete blood cell count (CBC) is one of the most frequently ordered lab-oratory tests in both the inpatient and outpa-tient settings. Not long ago, the CBC required peering through a microscope and counting the red blood cells, white blood cells, and platelets. These 3 numbers are still the primary purpose of the test. Now, with automated counters, the CBC report also contains other numbers that delin-eate characteristics of each cell type. For ex-ample:The mean corpuscular volume is the aver-age volume of red blood cells. Providers use it to classify anemia as either microcytic, normo-cytic, or macrocytic, each with its own differ-ential diagnosis. The differential white blood cell count provides absolute counts and relative percent-ages of each type of leukocyte.

The complete blood cell count (CBC) is one of the most frequently ordered laboratory tests, but some values included in the test may be overlooked. This brief re-view discusses 3 potentially underutilized components of the CBC: the red blood cell distribution width (RDW), the mean platelet volume (MPV), and the nucleated red blood cell (NRBC ...

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