Toxicity Testing Requirements, Methods and Proposed ...

Toxicity Testing requirements , Methods ANDPROPOSED ALTERNATIVESM egan Erin Gallagher*I. INTRODUCTIONT oxicology is the study of chemical substances that harm biologicalorganisms.' Toxic exposure can occur transdermally through contactwith the skin, orally and via Toxicity Testing is necessary toprovide some basis for the regulation of substances that humans andother living things may come into contact with, intentionally or not. It isused to determine the safety of cosmetics, pharmaceuticals, food addi-tives., pesticides, chemicals, additives and consumer products. A toxic ef-fect can result from a natural or a manufactured substance and manifesta variety of symptoms, both immediate and long-term.' As a result, tox-icity Testing introduces a variety of Methods and rates of exposure to thetest organism, in order to formulate a more accurate assessment of therisk of harm that the test substance may pose to human health and human knowledge of the Toxicity of various chemicals is theresult of animal research, though it is intended for the most part to extra-polate predicted human physiological Although there is noaccurate numerical statistic available, animals are used by the millionsannually for product Testing in the United States.

Toxicity Testing Requirements sponse data, and the adoption of alternative methods will bring benefits of accuracy, cost and time efficiency in addition to the reduction of animal suffering. II. FEDERAL TOXICITY TESTING REQUIREMENTS Toxicity testing is required by federal law in a variety of contexts.

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