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Understanding Diagnostic Tests - CancerEducation.com

11/9/20101 Understanding Diagnostic TestsSteven M. Horwitz AttendingLymphoma ServiceMemorial Sloan-Kettering Cancer CenterLymphomasDiagnosis and workup 2 of the most important initial questions What do you have? Where do you have it? Other important question What are you going to do about it?11/9/20102 LymphomasDiagnosis Biopsy of suspicious lymph nodes or masses (extranodal) Routine histology Immunophenotyping CD2, CD3,CD4, CD5, CD7, CD8, CD20, CD30, CD56, etc11/9/20103 Large CellsSmall CellsFollicularDiffuseArchitecture11/9/2 0104 Types of Biopsies Fine needle aspirate (FNA) Core Needle Biopsy Surgical: Incisional or excisionalTypes of BiopsiesFNAS mallest sampleBedside or hard to reachNo ArchitectureCoreHollow needleLess invasiveCT guidedSmall SampleSurgicalBest sam

11/9/2010 12 PET (CT) Scan, Fusion Images Nodule in the lung seen on CT scan. PET fusion images show that is it metabolically active and therefore more likely to be cancer-this requires a

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