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Understanding the Immune System: How it works - IMGT

Understanding the Immune system How It works DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH National Institute of Allergy and Infectious Diseases National Cancer Institute Understanding the Immune system How It works DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH National Institute of Allergy and Infectious Diseases National Cancer Institute NIH Publication No. 03-5423 September 2003 Contents 1 Introduction 2 Self and Nonself 3 The Structure of the Immune system 7 Immune Cells and Their Products 19 Mounting an Immune Response 24 Immunity: Natural and Acquired 28 Disorders of the Immune system 34 Immunology and Transplants 36 Immunity and Cancer 39 The Immune system and the Nervous system 40 Frontiers in Immunology 45 Summary 47 Glossary IntroductionThe Immune system is a network ofcells, tissues*, and organs that worktogether to defend the body against attacksby foreign invaders.

Introduction T he immune system is a network of cells, tissues*, and organs that work together to defend the body against attacks by “foreign” invaders. These are primarily

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