Transcription of University of Wisconsin Hospital and Clinics Guidelines ...
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University of Wisconsin Hospital and Clinics Guidelines ...
University of Wisconsin Hospital and Clinics Guidelines for Anti-Infective Lock Solutions Guidelines developed by UWHC Drug Policy Program Author: Marie Pietruszka, PharmD Reviewed by: Christopher Crnich, MD; Nasia Safdar, MD; Dennis Maki, MD; Antimicrobial Use Subcommittee Coordination: Sara Shull, PharmD, , Manager-Drug Policy Program, Lee Vermeulen, RPh, MS, FCCP, Director of Center for Clinical Knowledge Management. Approved by P&T: January 2011 Scheduled for Review: January 2013 Background Anti-infective lock solutions are used to prevent or treat device- related bacteremias that result from colonization of bacteria within the lumen of an intravascular device.
Device-related bloodstream infection (BSI) usually requires systemic antimicrobial therapy and catheter removal. 1. For needed long-term devices, catheter salvage is often desirable. The instillation of an anti-infective lock solution into the IVD has been studied for both prevention and treatment of long-term catheter-related bacteremia.
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