Transcription of Update on the Management of Refractory Coeliac …
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Update on the Management of Refractory Coeliac …
Management of Refractory Coeliac diseaseJ Gastrointestin Liver DisMarch 2007 No 1, 57-63 Address for correspondence:REVIEWSU pdate on the Management of Refractory Coeliac DiseaseAbdulbaqi Al-toma, Wieke HM Verbeek, Chris JJ MulderDepartment of Gastroenterology ,VU University Medical Center, Amsterdam, The NetherlandsProf. CJJ MulderUniversity Medical CenterDept. Box 70571005 MB Amsterdam, The NetherlandsE-mail: Refractory Coeliac disease (RCD) is being currentlydefined as persisting or recurring villous atrophy with crypthyperplasia and increased intraepithelial lymphocytes inspite of a strict gluten free diet for more than 12 months orwhen severe persisting symptoms necessitate interventionindependent of the duration of the dietary therapy.
Management of refractory coeliac disease 59 duodenal villous atrophy (16). A high index of suspicion for an overt lymphoma should lead to an extensive work-up
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