Updated guidelines on PEP for varicella/shingles
have varied from reporting no breakthrough varicella infections following aciclovir while others report a rate of 3–22%. [12] In a retrospective observational study evaluating the effectiveness of aciclovir post exposure prophylaxis in 141 contacts exposed to varicella in a paediatric setting between 2000 and 2007 in a Japanese hospital, the rate
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