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US-56427 ---------------------------- DOSAGE AND ...

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use BRILINTA safely and effectively. See full prescribing information for (ticagrelor) tablets, for oral use Initial Approval: 2011 WARNING: (A) BLEEDING RISK, and (B) ASPIRIN DOSE AND BRILINTA EFFECTIVENESS IN PATIENTS WITH ACSSee full prescribing information for complete boxed RISK BRILINTA, like other antiplatelet agents, can cause significant, sometimes fatal bleeding. ( , ) Do not use BRILINTA in patients with active pathological bleeding or a history of intracranial hemorrhage.

not start BRILINTA in patients undergoing urgent coronary artery bypass graft surgery (CABG). (5.1, 6.1) • If: possible, manage bleeding without discontinuing ----- BRILINTA. Stopping BRILINTA increases the risk of subsequent cardiovascular events. (5.4) ASPIRIN DOSE AND BRILINTA EFFECTIVENESS IN PATIENTS WITH ACS ...

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